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Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

Until properly designed, peer-reviewed human clinical trials are completedand an FDA-regulated production pathway existsclinicians should remain cautious and avoid its clinical use in patients

Either direction would significantly impact the peptide landscape

Written informed consent for participation in this study was provided by the participants legal guardians/next of kin