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In reality, weight loss can include a mix of: fat mass water shifts glycogen depletion lean body mass loss Lean mass includes more than skeletal muscle alone, but from a patient perspective, the concern is practical: if too much muscle is lost during weight reduction, people may feel weaker, recover worse, move less, and potentially struggle more with long-term metabolic maintenance
Semaglutide Side Effects & Risks Nausea & Digestive Symptoms: Many users experience nausea, vomiting, or constipation, particularly in the first few weeks
But if you are on medications with narrow therapeutic windows (like certain heart medications or blood thinners), discuss the potential implications with your provider
Benefits of Semaglutide for Insulin Resistance Patients Using semaglutide for insulin resistance patients offers several benefits
Secondly, significant weight loss and the resultant change in the inflammatory phenotype of obese adipose tissue would reduce the release into the circulation of key pro-fibrotic pro-inflammatory cytokines/adipokines such as TNF-, IL-6, leptin [31], visfatin and resistin, and increase levels of anti-fibrotic adipokines such as adiponectin [32]
