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Free Radic Biol Med 145:819
Incretin-based drugs and intestinal obstruction: a pharmacovigilance study
Furthermore, higher TMAO in chronic kidney disease patients was associated with a 2.8-fold increase in mortality risk [3]
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(B) Semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of uncoupling protein 1 (UCP1), mitochondrial biosynthesis, and thermogenic marker, or promote fatty browning through nitric oxide synthase (NOS), neuropeptides (NPs), sirtuin 1 (STRT1), signal transducer and activator of transcription 3 (STAT3), and bone morphogenetic protein 4 (BMP4) signaling
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