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Recognized for its efficacy, tirzepatide works by emulating the function of incretin hormones, which play a critical role in blood sugar regulation

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While strict inclusion criteria ensured methodological quality, they may have reduced the breadth of eligible evidence, limiting the scope of subgroup analyses and the generalizability of certain findings

The percentage of cells value was set to 0.25, the natural log fold-change threshold was set to 0.1 with an adjusted P value threshold set to 0.05 for both ligand and receptor