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Studies show PHAs do not cause as much irritation
8k, yellow bars), and a strong increase in UCK2 expression (Fig
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Effect of high glucose condition on glucose metabolism in primary astrocytes
Simultaneous quantification of these two oxidized metabolites by electrochemical HPLC assay demonstrated that human P450 2E1 selectively oxidizes APAP to NAPQI (determined as glutathione conjugate, GS-APAP), whereas human P450 2A6 selectively oxidizes APAP to 3-OH-APAP (Chen et al., 1998)
