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(2) Tkalcevi VI, Cuzi S, Brajsa K, Mildner B, Bokuli A, Situm K, Perovi D, Glojnari I, Parnham MJ

Transcriptomic analysis identified key genes implicated in cadmium toxicity, providing mechanistic insight

B complex vitamins are composed of eight B vitamins: B-1 (thiamine): Thiamine is one of the key nutrients involved in the process of converting food into energy

Conversely, after APAP injection in hepatic specific PGC-1 overexpressing mice, the high expression of primary ROS scavengers is not able to counteract the hepatic oxidative stress induced by APAP, due to the collapse of GSH reservoir caused by the lowered Gcl-c expression and by the massive utilization of GSH for NAPQI detoxification performed by Glutathione S-Transferases

Because toll-like receptor-4 (TLR4) is a receptor for LPS, subsequent experiments were conducted using TLR4 knockout (TLR4KO) mice