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Extending beyond local gut effects, probiotics profoundly influence systemic immunity by interfacing with gut-associated lymphoid tissue, where strain-specific interactions with dendritic cells and macrophages in Peyers patches drive regulatory T-cell differentiation and elevate anti-inflammatory cytokines such as interleukin-10 (IL-10) and transforming growth factor-beta [15]
Additionally, it counteracted colorectal cancer in a mouse model, increasing anti-inflammatory cells (CD4 + Tregs and CD4 + IL-10 + cells), and decreased pro-inflammatory cells such as T helper (Th)1 and Th17 cells (342)
Same implications for semaglutide compounding
Jain, A
Liposomal encapsulation protects the glutathione from this breakdown, allowing more of the molecule to reach the intestinal wall intact
