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Examples of proteins having a quaternary (or quartary) structure include hemoglobin, HIV-1 protease and the insulin hexamer

J.GaoY.et al (2021b)

Another study published in Diabetes Care showed that combining semaglutide with vitamin B12 supplementation led to improvements in insulin sensitivity and glucose metabolism, making it an effective option for individuals with prediabetes or type 2 diabetes

It is important not to self-treat with high-dose B12 supplements before seeing your GP if you suspect deficiency, as this can interfere with diagnostic blood tests and potentially mask underlying conditions such as pernicious anaemia

Panigrahi P, Parida S, Nanda NC et al (2017) A randomized synbiotic trial to prevent sepsis among infants in rural India