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This protection is mediated through mechanisms such as competition for nutrients and attachment sites, as well as the production of antimicrobial compounds
New indication strategies are most powerful when they expand a drug into a much larger patient population or when the new indication is clinically significant enough to justify premium pricing that erodes more slowly than the original indications market
Cardiovascular diseases, including heart disease and stroke, which are the first and third leading causes of death for both men and women in the United States, account for 1 in 3 of all U.S
Rare side effects can include muscle weakness in uremic patients and seizures in people with seizure disorders
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