In REDEFINE 2, which included participants with type 2 diabetes (a population that typically shows lower weight loss with any intervention), CagriSema achieved 13.7% weight loss compared to 3.4% with placebo
The oral form uses a SNAC (sodium N-[8-(2-hydroxybenzoyl)amino]caprylate) absorption enhancer to allow GLP-1 passage through the gastric mucosa, achieving approximately 1% bioavailability compared to subcutaneous injection
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Again, we're sort of altering our body, right
Below is the exact method behind your result, so you can see where every number comes from, starting with your Basal Metabolic Rate (the calories your body burns at rest), estimated with the revised Harris-Benedict equation