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Signs of more severe dehydration include (9): Little to no urination, or very dark yellow or amber-colored urine Dry, shriveled-looking skin Dizziness or lightheadedness Irritability or confusion Rapid heartbeat Rapid breathing Sunken eyes Extreme tiredness or listlessness In severe cases, shock or loss of consciousness Spotting these signs early can help you take action before dehydration becomes a bigger issue, especially if youre managing side effects from GLP-1 medications

The half-life problem: why 2 days early creates overlap Half-life is the time it takes for half of a drug to be eliminated from your body

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HR, 1.97

The highest levels of GSH are found in our heart, muscle tissues and the liver