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After intravenous administration, the cumulative excretion rates of ASD in the urine and bile were 14.79 1.87%, and 21.76 17.61% respectively, but only 0.011% in feces, suggesting that the urine and bile were the main excretion pathways and that there was a large amount of biotransformation in the gastrointestinal tract
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimers disease
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