Its rising prominence in skincare formulations is attributed to its robust antioxidant properties, known for brightening skin tone, diminishing the appearance of fine lines and wrinkles, and enhancing overall skin health
It was discovered in the saliva of the Gila monster, a venomous lizard found in the American southwest, although no one knows why the lizard produces a molecule that replicates the action of GLP-1 when injected twice a day
In addition, L-carnitine caused higher glycogen deposition in the fasting state, and increased and decreased the mRNA expressions of gluconeogenesis-related and glycolysis-related genes, respectively
However, they need further evidence-based studies
The peer-reviewed literature is also concentrated within a single research group (Watowich lab, University of Texas at Austin) and its industry partner Ridgeline Therapeutics, with limited independent replication to date