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It is unknown whether tirzepatide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as the human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined
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Data analysed by one-way ANOVA, multiple comparison, Bonferroni post hoc test ( f , g , j , l - n , r and s ), two-way repeated measures ANOVA to assess main effects of treatment ( b , c , e and k ), and ANCOVA computed with calR using body weight as a covariate ( p )
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