In skeletal muscle, IGF-1 LR3 activates satellite cells, promoting their proliferation and differentiation into mature muscle fibersa process termed hyperplasia (increase in cell number) distinct from hypertrophy (increase in cell size)
Medical experts warn that such treatments, especially during fasting, can put immense strain on the heart
This story mentions weight, weight loss, and/or prescription GLP-1 drugs, which are FDA-approved for weight management in adults diagnosed with obesity or with overweight and at least one weight-related health condition
Semin Arthritis Rheum 30:8799 Murphy R, McConell G, Cameron-Smith D et al (2001) Creatine transporter protein content, localization, and gene expression in rat skeletal muscle
This is obviously prescribed off label by physicians, but keep in mind as with the other peptides in this pathway, Vilise will stimulate pigmentation