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In some of the large-scale clinical studies evaluating the safety of GLP-1RAs against CV disease, the effect on kidneys was evaluated as a secondary endpoint

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Subsequently, further stratification by folate status in the case of the MTHFR models or by cobalamin status in the case of the MTRR models was performed to investigate whether low or normalhigh folate or cobalamin status affects the association between the polymorphisms and tHcy

The functional classification of these differentially expressed genes can help us better determine the potential pharmacological mechanisms of the two drugs

(2) provide information on the existing methods for protecting Met in the rumen