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Oncogene 22 , 72657279 (2003)

Its efficacy is especially notable in individuals experiencing age-related cognitive decline, mild cognitive impairment, and even those with early-stage Alzheimer's disease

High doses may amplify the risk of adverse effects, including digestive and cardiovascular issues

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Cross-model transcriptomic convergence reveals common molecular signatures of early-life adversity Building on our previous finding that low-dose PFE induces persistent affective deficits and mesolimbic circuit disruption [25], we next examined whether behavioral similarities across prenatal THC, stress, and fentanyl exposures reflected transcriptomic convergence