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Analysis of GLP-1 receptor expression in the cerebral cortex and ex vivo experiments demonstrated a potent dilatory effect on cortical arterioles, suggesting the potential for improved brain perfusion with the administration of GLP-1 RAs
Key takeaways Victoza (liraglutide) is an injectable GLP-1 agonist, while Jardiance (empagliflozin) is an oral SGLT2 inhibitor
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DOI: 10.1016/j.freeradbiomed.2019.02.009
McMurray JJV, Solomon SD, Inzucchi SE, Kober L, Kosiborod MN, Martinez FA, Ponikowski P, Sabatine MS, Anand IS, Belohlavek J, Bohm M, Chiang CE, Chopra VK, de Boer RA, Desai AS, Diez M, Drozdz J, Dukat A, Ge J, Howlett JG, Katova T, Kitakaze M, Ljungman CEA, Merkely B, Nicolau JC, OMeara E, Petrie MC, Vinh PN, Schou M, Tereshchenko S, Verma S, Held C, DeMets DL, Docherty KF, Jhund PS, Bengtsson O, Sjostrand M, Langkilde AM
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