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The peptide appears to interact with the dopaminergic and serotonergic systems, which may contribute to its effects on pain perception and mood

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PLoS Med 3(4):e101 Imperato A, Di Chiara G (1986) Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol

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Its mechanism also carries meaningful antioxidant and anti-inflammatory activity, tied to how the tripeptide handles copper in oxidative stress contexts, neutralizing lipid peroxidation byproducts and reducing inflammatory mediators