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A TE ADA+ patient was identified if an evaluable patient had either of the following: Baseline status of ADA not present and at least 1 postbaseline status of ADA present with titer 2 or more times the minimum required dilution of the ADA assay, or Baseline and postbaseline status of ADA present, with the postbaseline titer being greater than or equal to 4-fold than the baseline titer

At minimum, screening should include depression and suicidal ideation

Patients experiencing severe abdominal pain, persistent vomiting, signs of infection, or allergic reactions should seek urgent medical attention

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Lilly showed in recently announced clinical trial results that patients who switched to orforglipron after losing weight on either Wegovy or Zepbound regained less weight than participants who switched to a placebo