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Tirzepatide (e.g., Mounjaro) Mechanism: Tirzepatide is a dual agonist that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide), offering a two-pronged approach to appetite suppression and insulin regulation

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Resident cardiac macrophages in the atrioventricular node maintain direct contact with cardiomyocytes through gap junctions

People taking the Wegovy pill lost an average of about 14% of their body weight in studies, compared to about 19% with the injection when a person steps up to the 7.2 mg highest dose