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This review focuses on six commonly abused drugs (Table 1), classified based on their pharmacological and neurotoxic profiles: Psychostimulants: Methamphetamine (METH), cocaine and synthetic cathinones (bath salts) primarily act on monoaminergic systems, leading to disruptions in dopamine, serotonin, and norepinephrine signaling (Sulzer et al., 1995

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Boys, however, have only one copy of the gene, which they inherit from the mother

Alcohol disrupts the gut barrier and antagonizes the very process the probiotic is trying to support

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