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FADD, via its death effector domain activates initiator caspase-8, which subsequently activates effector caspases (caspase-3, -6, and -7), culminating in apoptotic cell death (96, 99101)

Huang Q, Liao J, Li J, Gu Z, Zhang X, Sun M, Meng W, Mao G, Pei Z, Zhang S, Li S, Zhang C, Wang Y, Liu J, Shu T, Tao M, Lu Y, Xiao K, Xu Q, Lu J (2025) Curcumin-loaded Ceria nanoenzymes for dual-action suppression of inflammation and alleviation of oxidative damage in the treatment of acute lung injury

extrapolating it into a claim of clean human endocrine selectivity is not supported

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