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The withdrawal experience varies significantly among individuals

Endocrinology and metabolism 298 , E751E760, doi: 10.1152/ajpendo.00745.2009 (2010)

Options include metoclopramide (restricted to maximum 5 days' use due to risk of neurological side effects), prochlorperazine (which may cause drowsiness and anticholinergic effects), or ondansetron (which can cause constipation and has QT-interval prolongation risks in some patients)

Among adolescents, the rate of use rose six-fold among boys and nearly seven-fold among girls, and among young adults the uptick in use was close to five-fold among men and almost eight-fold among women, the study found

(PubMed) Coronel F, Tornero F, Torrente J, et al