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Research Gaps Based on the mapped evidence from the 18 included interventional studies (15-32), several notable research gaps were identified, underscoring the need for more rigorous and standardized investigations in the field of pharmacological and nutraceutical interventions for chronic hemodialysis complications

Phase 3 (21 Days) Deep Tissue Repair: Complete healing of joint micro-injuries occurs as new, healthy tissue regenerates, restoring long-term joint health

Generic liraglutide has been available since 2024 ( [68] ), and semaglutides US patent exclusivity is set to expire on March 20, 2026, which could further reshape the competitive landscape

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