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Providers increasingly encounter patients Read More Protecting Muscle While Treating Obesity: New Protein Targets for Older Adults on GLP-1s Jun 16, 2026 Articles, Diet and Nutrition, Exercise, Geriatric Medicine, GLP- 1 Agonist Therapy Center, GLP-1 Agonist Therapy Center, Obesity, Obesity 1,783 views The rise of highly effective GLP-1 receptor agonists and dual incretin therapies has transformed obesity treatment
NHS England rolled out tirzepatide for weight management in cohorts after NICE TA1026 in December 2024: 3 Cohort 1 (from June 2025): adults with a body mass index (BMI) of 40 or higher and at least four of five weight-related conditions (type 2 diabetes, hypertension, dyslipidaemia, obstructive sleep apnoea, cardiovascular disease)
They work through entirely different mechanisms and have very different risk profiles
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