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These endothelial abnormalities may account for the impaired left ventricular relaxation observed in pressure-overload hypertrophy [18]
The broader receptor activity of tirzepatide may contribute to slightly higher rates of early gastrointestinal intolerance, although discontinuation rates remain comparable 7
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It slows down the breakdown of collagen and elastin, essential proteins for skin structure and elasticity, thereby preventing premature aging
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