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Concerning the gonadal profile, no changes were detected in any of the reproductive endpoints after treatment with the lower doses of the poly-agonists (Suppl

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This makes them relatively safe from a hypoglycaemia perspective, particularly when compared to sulphonylureas or insulin therapy

Conclusion This study demonstrates the technical feasibility of SLACS-based spatial transcriptomic profiling in human VAT, with exploratory biological findings that warrant validation in larger cohorts

As peptide medications age after opening, they may lose potency and become less predictable