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For weight management in the UK, NICE-approved options are limited to orlistat (available over-the-counter or on prescription) and, within specialist weight management services, liraglutide 3.0mg (Saxenda) or semaglutide 2.4mg (Wegovy) with their specific continuation criteria
M., Malek, R
The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation
Below are highlights from the most significant published studies
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