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Nat Rev Cancer (2015) 15:96109
A mismatch between the symptoms and the laboratory result is a reason to widen the evaluation
Originally, the Schilling test was used for this purpose, but it is no longer used in view of the safety factors related to the use of radioactive B12 ( 57 Cocyanocobalamin) (Sobczynska-Malefora et al., 2021)
In many cases, what is interpreted as angiogenic activity may instead reflect other forms of vascular remodelingsuch as BBB disruption, pericyte loss, or basement membrane alterationsrather than true neovascularization
With 2.5 mL BAC water, the Low Dose is 1.6 mg (5 units) and the Elevated Dose is 4.8 mg (15 units)
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