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(2.2, 8.7) Renal impairment: Consider reducing the dose and/or frequency

However, I did read the fine print on the bottom of their landing page that cited a REVISE study from the National Library of Medicine

For patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of JANUVIA is 25 mg once daily

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The plan includes some quick prep sections for days when you might have less energy (common when starting the medication)