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These findings suggest the potential use of GLP1R agonists, such as exendin4, in therapies for spinal cord injuries and possible chronic neuroinflammatory disorders (116)

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TGF- secreted by tumor vascular endothelial cells can induce differentiation of endothelial cells and adjacent fibroblasts into myofibroblasts through both autocrine and paracrine mechanisms (193)

As a next step, researchers are conducting a subgroup analysis to understand how different patient cohorts respond to the drugs