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For example, ALF has a 1A status on the transplant waitlist, whereas acute-on-chronic liver failure is presently given no priority and the patient is placed on the list according to the MELD score.10 Epidemiology ALF is considered a relatively rare disease, with an annual incidence of 2,000 to 3,000 cases per year.1 It accounts for 4 to 5% of all liver transplants