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We also observed increased tissue weights for heart and kidneys in female but not male SKO mice, consistent with previously reported organomegaly in this model (35)

Glucagon-like peptide-1, or GLP-1, is a hormone that helps regulate blood sugar, manage appetite, and support digestion

GLP-1 drugs appear to have direct protective effects on the cardiovascular system, reducing inflammation, improving endothelial function, and potentially stabilizing atherosclerotic plaques