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For example, structural studies have shown that all ghrelin receptor agonists, regardless of ligand type, are accommodated within the bifurcated pocket, similar to Compound 21
Chang CH et al
For example, when using RSL3a canonical ferroptosis inducer through inhibition of GPx4GPx1 cannot compensate for the loss of GPx4 since its main substrates are hydroperoxides whereas GPx4 reduces lipid peroxides [19]
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