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ROS levels allow the activation of pro-tumorigenic signaling pathways without induced cell death [12, 17]
ESC functions as an antioxidant through dual mechanisms: direct ROS scavenging via hydroxyl groups at positions 6 and 7 of the coumarin ring, which donate electrons to ROS, converting them to inert products, and indirect antioxidant upregulation via Nrf2/ARE pathway activation
Researchers have also found that glutathione is an important factor when it comes to healthy aging and supporting long-term physiological function
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Drug Treatments Treatments of OC cell lines with 2.5 - 20 M erastin, an inhibitor of GSH synthesis, or 0.5% DMSO as control were performed in Dulbeccos modified medium containing 10% FBS and 1% penicillin/streptomycin
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