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Oxidative stress results when reactive forms of oxygen are produced faster than they can be safely neutralized by antioxidant mechanisms and/or from a decrease in antioxidant defense, which may lead to damage of biological macromolecules and disruption of normal metabolism and physiology [5]
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References For Further Reading (1) H.Wessells, V.J.Hruby, J.Hackett, et al (2003) Ac-Nle-cAsp-His-DPhe-Arg-Trp-Lys-NH2 induces penile erection via brain and spinal melanocortin receptors Neuroscience, 2003;118(3):755-62 (2) R.C.Rosen, L.E.Diamond, D C Earle, et al (2004) Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra International Journal of Impotence Research, 2004 Apr;16(2):135-42