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Methylcobalamin degrades more rapidly
Helps treat Vitamin B12 deficiency and anemia
For people who cannot tolerate GI side effects or who have medical conditions that make GLP-1 agonists risky, this safety differential is not a minor footnote
A 2021 review in Nature Reviews Molecular Cell Biology describes a gradual drop in tissue and cellular NAD+ across aging in rodents and humans, and links that fall to metabolic disease, cognitive decline, and sarcopenia [1]
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