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There are only two reasons to stop a clinical trial in the middle, Bob Seevers, a former FDA reviewer, now a regulatory consultant, tells Outside Run

A 2019 network meta-analysis of 233 trials (n = 147,710) reported elevated risks of dizziness (odds ratios [ORs] 1.92, 1.57, 1.40) and headache (ORs 1.34, 1.41, 1.18) with GLP-1 RAs versus insulin, thiazolidinediones, and placebo 40