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ADJUNCT ONE was a 52-week, double-blind, treat-to-target study conducted in 1398 people randomised 3:1 to receive liraglutide (1.8 mg, 1.2 mg or 0.6 mg) or placebo, in 177 centres in 17 countries (Mathieu et al, 2016)

Treatment plans should always remain individualized

While Semaglutide/GLP-1 and Liraglutide are both GLP-1 agonists, they should not be used together

See our overview of medical weight management options for evidence-based non-surgical interventions, or learn about our bariatric surgery for severe obesity program for patients with BMI 35+

Key takeaways Health insurers face several key considerations and challenges around approval and reimbursement of GLP-1s