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Lightheadedness is not a direct pharmacological effect listed in FDA labeling but occurs indirectly through hypoglycemia (especially with insulin or sulfonylureas), dehydration from gastrointestinal side effects, or orthostatic hypotension related to weight loss and metabolic changes
Finally, although most of the evidence of a potential benefit of GLP-1 RAs in HF originates from CVOTs in type 2 diabetes, it may likely be in the weight management setting that the drug class could be of the highest clinical value, particularly in people with HFpEF
J Neurochem (2018) 146(2):17385
GLP-1 receptors exist throughout the digestive tract, not just in the stomach
Rotate placement to avoid skin sensitivity
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