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All experiments were conducted in a buffer solution containing 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM dithiothreitol (DTT), and 5% dimethyl sulfoxide (DMSO)
Alternately, Cys-Gly or bis-Cys-Gly can catabolized by membrane bound peptidases to yield cysteine (or cystine) and glycine
Animal models of Parkinsons disease have shown that treatment with semaglutide can restore dopamine levels and alleviate symptoms
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