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Time will tell how the GLP-1 agonist saga unfolds
The picture is consistent: the adverse events are overwhelmingly gastrointestinal, they track with dose, and they cluster during escalation
Are metformin and Glucophage (metformin) the same drug?
Ligand specificity GLP-2 and GLP-1 share high sequence similarity (69.7%) and have almost identical residues in two regions: the N-terminus (first six residues in GLP-2) that penetrates into the TMD core, and the C-terminus (residues 1833) that is recognized by the ECD and ECL1 of the receptor
Waste Removal: It also helps remove toxic waste products that build up inside the engine during energy production, preventing cell damage
