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Notably, citrulline supplementation restores fibroblast activation under arginine-deprived conditions, whereas ornithine and glutamine provide essential precursors for polyamine biosynthesis in fibroblasts [50]
Imbalances between GABAergic and glutamatergic neurotransmission and increased oxidative stress together with altered glutathione (GSH) metabolism have been hypothesized to play a role in both VPA-induced embriotoxicity and in human ASD
doi: 10.4103/2394-2916.193515
True copper allergy typically produces hives, swelling, or systemic symptoms beyond localized skin changes
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