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The mechanisms of GLP-1 to improve NAFLD include improving lipid metabolism by regulating metabolism-related signaling pathways such as AMPK pathway [33] and JNK pathway [105]

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The detection of HSMGSH in cells not exposed to exogenous FA indicates that cellular metabolism continuously produces sufficient FA to react with GSH yielding HSMGSH (Fig

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regulates the proliferation, migration, and apoptosis of ECs, promoting endothelial repair under physiological conditions but potentially causing endothelial dysfunction under pathological conditions

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