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In contrast, GAA and the ferroptosis inhibitor liproxstatin-1 (Lip-1) significantly activated the NRF2/SLC7A11/GPX4 signaling pathway and mitigated A 25-35 -induced neuronal injury (Lu et al., 2025)

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Finally, we note that the model predicts modest decreases in the rate of the DNA methylation reaction (vDNMT) and this is consistent with the reported global DNA hypomethylation seen in autistic children [73]