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What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug
In general, peptides are very well-tolerated
Low-dose naltrexone is relatively cheap and widely available
The 2020 report on Atypical shoulder pain and dysfunction following inactivated influenza vaccine, Vaccine Adverse Event Reporting System, states that over 80% of all injuries suffered were cited from the vaccination being administered "too high." Such improper placement can cause an inflammatory response, resulting in localized soreness
While BPC-157 has a strong safety record in animal studies, there are currently no long-duration, placebo-controlled human trials available to confirm its effects over months or years
