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Both cell lines were established and characterized by Gold et al (17)
132,133 A recent in vitro DDI study of ATSP-7041, a stapled -helical peptide being developed as an anticancer agent, revealed minimal CYP inhibition
These preclinical findings enhance understanding of how SFN could exert neuroprotective and anti-inflammatory effects relevant to ASD treatment
Dose-related effects on the rat fetus (structural abnormalities and reduced body weight) occurred only at higher dosages, equal to or greater than 150 mg/kg (more than 2344-times the 10 mg clinical dose, based on AUC), which were associated with maternal toxicity
a growing body of evidence has indicated that U0126 exerts its antioxidative activity through the MAPK/ERK-independent pathway 37
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