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The findings offer new insight into preventing rebound weight gain, a common side effect of stopping GLP-1 drugs for weight loss
Since a 10mg vial provides weeks of doses, bacteriostatic water with its benzyl alcohol preservative is the only safe choice for multi-dose reconstitution
Some GLP-1 medications require re-titration (restarting at a lower dose) after prolonged interruptionsfor example, liraglutide (Saxenda) requires re-titration if missed for more than 3 days, and semaglutide (Wegovy) may need re-titration after multiple missed doses
At the 12mg dose specifically, participants averaged 9.8% weight loss by week 12, which translates to roughly 20-25 pounds for someone starting at 220 pounds
Draw your dose quickly, return the vial to the refrigerator immediately, and never leave a reconstituted vial on a countertop or in a travel bag for extended periods
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