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While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]
Conclusion Whether you take it in the morning, evening, on an empty stomach, or with vitamin C, the key is consistency in your supplementation
It also plays a role in the growth of neurites, synapse formation, and signal transmission between neurons in the early stages of brain development (119)
Exogenous GH can create a more sustained, elevated level (a bleed), which poses a greater, more constant challenge to insulin sensitivity
